Catherine F. Siengsukon, P.T., Ph.D., Mayis Aldughmi, P.T., Ph.D., Melike Kahya, P.T., Sharon Lynch, M.D., Jared Bruce, Ph.D., Morgan Glusman, M.A., Abigail Ness Norouzinia, M.A., Sandra Billinger, P.T., Ph.D.
Disability and Health Journal, Volume 11, Issue 1, January 2018, Pages 116-121
DOI: https://doi.org/10.1016/j.dhjo.2017.04.011
Background
Sleep disturbances are common in individuals with Multiple Sclerosis (MS), but the impact of poor sleep quality on cognitive and physical function in individuals with MS is less clear.
Objective/Hypothesis: The purpose of this study was to examine the relationship between sleep quality and cognitive and physical function in individuals with mild MS.
Methods
Forty individuals with relapsing-remitting or secondary-progressive MS (50.3 ± 11.6 years of age) participated. The Pittsburgh Sleep Quality Index (PSQI) was used to index sleep quality. A PSQI of ≤5 was considered good sleep quality and >5 was considered poor sleep quality. Cognitive function was assessed using a battery of cognitive tests, and physical function was assessed using 2 objective measures and a self-report measure.
Results
Thirteen individuals (32.5%) indicated good sleep quality and 27 (67.5%) of the participants reported poor sleep quality. Those with good sleep quality performed significantly better on a visuospatial memory test (p = 0.025) and reported higher functional abilities (p < 0.001) compared to those with poor sleep quality. There was no difference in performance on the cognitive tests of verbal memory, information processing, or executive function, or the objective function measures. Individuals with poor sleep quality had higher levels of fatigue, depression, and anxiety, and lower quality of life.
Conclusions
Visuospatial memory appears to be the memory domain particularly associated with poor sleep quality in people with mild MS. Also, individuals with mild MS with poor sleep quality may underestimate their functional abilities.